Title: | A Versatile Shiny App for Microbiota Profiling in Clinical Microbiology |
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Description: | A Shiny web application offering a user-friendly, accessible, and reproducible platform for downstream analysis of 16S rRNA-based metagenomics data. Key features include quality control visualizations (e.g., rarefaction curves), community composition plots, and statistical analyses for alpha- and beta-diversity. The app integrates advanced features like community typing with Dirichlet multinomial modeling (DMM) and metadata-driven redundancy analysis (RDA) to explore microbial associations with clinical and experimental variables. |
Authors: | Sedreh Nassirnia [aut, cre] |
Maintainer: | Sedreh Nassirnia <[email protected]> |
License: | GPL-3 |
Version: | 0.1.0 |
Built: | 2024-12-20 06:33:56 UTC |
Source: | https://github.com/metagenlab/zAMPExplorer |
zAMPExplorer provides an interactive interface for analyzing and visualizing microbiome sequencing data, particularly the output of the zAMP pipeline (phyloseq objects). It includes functionalities such as: compositional barplots, heatmaps, diversity metrics, beta-diversity analyses, and more.
zAMPExplorer_app( onStart = NULL, options = list(), enableBookmarking = NULL, uiPattern = "/", ... )
zAMPExplorer_app( onStart = NULL, options = list(), enableBookmarking = NULL, uiPattern = "/", ... )
onStart |
A function that will be called before the app is actually run.
This is only needed for |
options |
Named options that should be passed to the |
enableBookmarking |
Can be one of |
uiPattern |
A regular expression that will be applied to each |
... |
Arguments to pass to golem options. See |
A shiny.appobj
object representing the running Shiny application.
Read QC, Taxa overviews.
Compositional barplots, relative abundance heatmaps.
Alpha and beta diversity visualizations.
Differential abundance testing using MaAsLin2.
Community typing using Dirichlet Multinomial Mixtures.
Interactive RDA ordination plots.
Useful links:
Documentation: https://github.com/metagenlab/zAMPExplorer
zAMP pipeline: https://zamp.readthedocs.io/en/latest/
if (interactive()) { zAMPExplorer_app() }
if (interactive()) { zAMPExplorer_app() }